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To order to select the name of reaction mechanism from the given list you should be know the Cleland nomenclature.

Other way of a choice of the mechanism can be used. You enter number of substrates, number of products and reaction mechanism category. The maximum number of reaction reactants in one direction can be equal three (sometimes four).
The order of bind of substrates and release products within the reaction sequence is described as follows. Mechanisms where all substrates must add to the enzyme before any products are released will be designated "sequential". Such mechanisms are called "Ordered" (for example, Ordered Bi Bi ) if the substrate add in obligatory order and the products leave similary, and "Random" (for example, Random Bi Bi) if the substrates do not react in obligatory order. When one or more products are released before all substrates have binded to the enzyme, the enzyme exist in two or more stable forms between which it oscillates during the reaction. Such mechanisms are called "Ping-Pong" (for example, Ping-Pong Bi Bi). If there is no central complex formed at all, as in the mechanism proposed by Theorell and Chance for alcohol dehydrogenase (see more in H.Theorell and B.Chance, Acta Chem. Scand., 1951, v.5, p.1127) the mechanism is called "Theorell Chance" (see example here ) mechanism.




Russian Academy of Science
Institute of Theoretical and Experimental Biophysics
Laboratory of Metabolic Simulation and Bioinformatics
Pushchino, Moscow reg., Russia, 142290.

Created by Milya Galimova.